Izvestiya of Saratov University.

Mathematics. Mechanics. Informatics

ISSN 1816-9791 (Print)
ISSN 2541-9005 (Online)

For citation:

Dol A. V., Gulyaeva A. O., Falkovich A. S., Maystrenko D. N., Generalov M. I., Solovyov A. V., Terin D. V., Lemeshkin M. O. Development and approbation of a mobile test bench for mechanical uniaxial compression testing of biological tissues. Izvestiya of Saratov University. Mathematics. Mechanics. Informatics, 2023, vol. 23, iss. 4, pp. 472-481. DOI: 10.18500/1816-9791-2023-23-4-472-481, EDN: IWZXSA

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Published online: 
30.11.2023
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Language: 
English
Heading: 
Mechanics
Article type: 
Article
UDC: 
531/534:[57+61]
DOI: 
10.18500/1816-9791-2023-23-4-472-481
EDN: 
IWZXSA

Development and approbation of a mobile test bench for mechanical uniaxial compression testing of biological tissues

Autors: 
Dol Alexander V., Saratov State University
Gulyaeva Alena O., Saratov State University
Falkovich Alexander Savelievich, Saratov State University
Maystrenko Dmitry N., Russian Scientific Center for Radiology and Surgical Technologies named after Academician A. M. Granov
Generalov Michail I., Russian Scientific Center for Radiology and Surgical Technologies named after Academician A. M. Granov
Solovyov Alexey V., Vsevolozhsk Clinical Interdistrict Hospital
Terin Denis V., Saratov State University
Lemeshkin Maxim O., Saratov State University
Abstract: 

A technique and a prototype of a mobile test bench for conducting experiments on uniaxial compression of biological tissue samples have been developed. The test bench consists of high-precision scales, an electronic caliper with modified grips, and a video camera. With the help of the test bench, a series of experiments (120 in total) was carried out to determine Young's modulus of atherosclerotic plaques and vascular walls removed from the human body no later than a few hours. A database of plaques and artery walls' mechanical characteristics, as close as possible to their real strength properties, has been formed. In addition, regression dependencies linking Hounsfield units and Young’s moduli of atherosclerotic plaques were constructed. The uniaxial compression technique has been verified on the Instron 3342 universal testing machine. Also, to demonstrate the applicability of the developed technique and test bench for uniaxial compression of hard tissues, experiments were conducted with 14 samples of bovine spongy bone.

Key words: 
biomechanics
atherosclerosis
mobile test bench
compression
Young’s modulus
Acknowledgments: 
There is no conflict of interest. The work was carried out within the framework of the State Assignment (project No. FSRR-2023-0009). The work was also supported by Vladimir Potanin Charitable Foundation (project No. GSAD-0013/23). The study was approved by the Ethics Committee of the Federal State Budgetary Institution “Russian Scientific Center for Radiology and Surgical Technologies named after Academician A. M. Granov” (Protocol No. 01-03/2023 from 30.03.2023).
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Received: 
23.08.2023
Accepted: 
28.09.2023
Published: 
30.11.2023
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