Izvestiya of Saratov University.

Mathematics. Mechanics. Informatics

ISSN 1816-9791 (Print)
ISSN 2541-9005 (Online)

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Dol A. V., Gulyaeva A. O., Falkovich A. S., Maystrenko D. N., Generalov M. I., Solovyov A. V., Terin D. V., Lemeshkin M. O. Development and approbation of a mobile test bench for mechanical uniaxial compression testing of biological tissues. Izvestiya of Saratov University. Mathematics. Mechanics. Informatics, 2023, vol. 23, iss. 4, pp. 472-481. DOI: 10.18500/1816-9791-2023-23-4-472-481, EDN: IWZXSA

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Development and approbation of a mobile test bench for mechanical uniaxial compression testing of biological tissues

Dol Alexander V., Saratov State University
Gulyaeva Alena O., Saratov State University
Falkovich Alexander Savelievich, Saratov State University
Maystrenko Dmitry N., Russian Scientific Center for Radiology and Surgical Technologies named after Academician A. M. Granov
Generalov Michail I., Russian Scientific Center for Radiology and Surgical Technologies named after Academician A. M. Granov
Solovyov Alexey V., Vsevolozhsk Clinical Interdistrict Hospital
Terin Denis V., Saratov State University
Lemeshkin Maxim O., Saratov State University

A technique and a prototype of a mobile test bench for conducting experiments on uniaxial compression of biological tissue samples have been developed. The test bench consists of high-precision scales, an electronic caliper with modified grips, and a video camera. With the help of the test bench, a series of experiments (120 in total) was carried out to determine Young's modulus of atherosclerotic plaques and vascular walls removed from the human body no later than a few hours. A database of plaques and artery walls' mechanical characteristics, as close as possible to their real strength properties, has been formed. In addition, regression dependencies linking Hounsfield units and Young’s moduli of atherosclerotic plaques were constructed. The uniaxial compression technique has been verified on the Instron 3342 universal testing machine. Also, to demonstrate the applicability of the developed technique and test bench for uniaxial compression of hard tissues, experiments were conducted with 14 samples of bovine spongy bone.

There is no conflict of interest. The work was carried out within the framework of the State Assignment (project No. FSRR-2023-0009). The work was also supported by Vladimir Potanin Charitable Foundation (project No. GSAD-0013/23). The study was approved by the Ethics Committee of the Federal State Budgetary Institution “Russian Scientific Center for Radiology and Surgical Technologies named after Academician A. M. Granov” (Protocol No. 01-03/2023 from 30.03.2023).
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